Four companies, four completely different price tags, all selling roughly the same pitch: pay us, and we’ll help you live longer. One membership costs less than a year of a mid-tier streaming bundle. Another costs more than most Americans’ annual take-home pay. Between them sits a 400-times price gap for services that, on the marketing page, sound remarkably similar — “personalized,” “data-driven,” “proactive,” “precision.”
We picked four well-known, well-documented longevity clinic memberships — Fountain Life, Human Longevity, Superpower, and Next Health — and compared them against the same fixed criteria: real 2026 pricing, what’s actually included, how each makes money, and whether either company has published anything beyond a press release to back up its claims. We don’t sell memberships, and we have no paid or affiliate relationship with any provider in this comparison.
TL;DR
- Longevity clinic membership pricing spans roughly $199/year (Superpower) to $85,000/year (Fountain Life’s application-only EPIC tier) — a genuinely enormous range for overlapping marketing claims.
- Fountain Life and Human Longevity are built around imaging and genomics (full-body MRI, coronary CT angiography, whole genome sequencing); Superpower is a low-cost biomarker-testing platform with no imaging; Next Health leans heavily on IV therapy and wellness treatments with weaker evidence behind them.
- Fountain Life’s headline outcome claims (a 13-to-1 ROI, 52% of fatty liver cases resolved) are self-published through press releases, not peer-reviewed studies.
- Physician-scientist Eric Topol has publicly written that longevity-marketing companies, named individually in his analysis, “have not yet provided any evidence for benefit” — a criticism aimed at this entire category, not one company.
- No clinic in this comparison has independent, peer-reviewed evidence that its membership extends life or reduces disease compared with standard care.
Quick Verdict
- Best for the most comprehensive diagnostics if budget isn’t a constraint: Fountain Life’s APEX tier ($21,500/year) — full-body MRI, coronary CT angiography with Cleerly AI plaque analysis, and blood biomarkers under one concierge membership.
- Best for the deepest single-visit workup: Human Longevity’s Health Nucleus — the only one of the four pairing whole genome sequencing with a same-day imaging and cardiac workup, at a steep price.
- Best value for straightforward biomarker tracking: Superpower, at $199/year — no imaging, but by far the cheapest way to get 100+ lab biomarkers and a health dashboard.
- Best if you specifically want IV therapy and recovery treatments alongside testing: Next Health — though its most-marketed treatments have the weakest independent evidence of the four clinics’ offerings.
- Who should skip all four for now: anyone expecting a membership fee to function as proof of a longer life. None of these companies have published controlled outcome data showing that.
Comparison Table
| Clinic | Price (as of 2026) | What’s included | Model | Locations | Pricing transparency | Published methodology |
|---|---|---|---|---|---|---|
| Fountain Life | CORE $10,500/yr; APEX $21,500/yr; EPIC $85,000/yr (application only) | CORE: quarterly labs + physician consults. APEX adds full-body MRI, coronary CT angiography with Cleerly AI, brain MRI, comprehensive blood panel, AI cancer screening, concierge access. | Annual membership, tiered | Multiple U.S. clinics (Florida, New York, and others) | Tiered pricing published online | Partial — self-published “real-world outcomes” (ROI, fatty liver resolution rates) via press release; not peer-reviewed |
| Human Longevity (Health Nucleus) | HNX: $4,950 initial / $2,950 renewal; HNX Platinum: $25,000 initial (3-yr) / $6,000 renewal | Whole genome sequencing, full-body MRI, coronary calcium score, echocardiogram, 2-week heart rhythm recording, metabolomics, gut microbiome testing, DEXA, cognitive testing, ~120 blood assays (varies by tier) | Membership with multi-year commitment | San Diego-based flagship, limited locations | Tiered pricing published online | Partial — company describes itself as data/research-oriented; specific criticized by independent researchers (below) for lacking outcome evidence |
| Superpower | $199/yr baseline; $399/yr (NY/NJ, expanded panel) | One annual blood draw, 100+ biomarkers, personalized health score and biological age estimate, on-demand care team access via app | Annual membership, single tier (add-ons cost extra) | Nationwide via Quest Diagnostics draw sites, or mobile phlebotomy for a fee | Published, single flat price | No — no published outcomes data found; product is fundamentally standard lab testing plus a proprietary dashboard |
| Next Health | Medicine 4.0: ~$99/mo; Premier 4.0: ~$299/mo; Platinum: pricing by inquiry | Quarterly biomarker testing + physician consults (Medicine 4.0); higher tiers add IV vitamin drips, vitamin shots, cryotherapy, infrared therapy, hyperbaric oxygen, InBody/VISIA scans | Monthly membership, tiered | Multiple U.S. locations (Los Angeles, New York, Miami, and others) | Tiered pricing published online | No — most heavily marketed treatments (HBOT, NAD+ IV, ozone) are off-label uses without longevity-specific published support |
Prices reflect publicly available information as of mid-2026 and are cited individually in the Sources section below. This market moves fast — confirm current pricing directly with each provider before joining.
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Fountain Life
Fountain Life is the newest and fastest-growing of the four, positioned squarely at the intersection of concierge medicine and consumer longevity marketing, with high-profile backers and repeated media coverage.
Pricing. Three tiers: CORE ($10,500/year — quarterly blood tests and physician consultations, no full-body imaging), APEX ($21,500/year — adding full-body MRI, coronary CT angiography read with Cleerly AI plaque analysis, brain MRI, an expanded blood panel, and AI-assisted cancer screening), and EPIC ($85,000/year, available by application only, with details not fully public).
Scale. The company says it has more than 8,000 members and has collected over 15 billion clinical data points across its membership base — a genuinely large dataset by the standards of this industry, though the figure comes from the company itself, not an independent audit.
What they publish. In December 2025 and January 2026, Fountain Life issued press releases reporting a 13-to-1 return on investment over ten years for its Executive Health Program, over $20 million in annual net benefit per 1,000 members, and a 52% resolution rate for fatty liver cases confirmed by follow-up MRI. These are notable numbers if accurate. They are also, as of this writing, self-reported through company press releases rather than published in a peer-reviewed journal or presented at an independent academic conference — a meaningfully different standard of evidence than, for example, a study submitted for peer review.
What they don’t disclose. Full methodology behind the “13-to-1 ROI” and “$20M annual benefit” figures — how net benefit was calculated, what counterfactual was used, and whether the cohort was independently verified — was not available in public materials at the time of writing.
ScanGlean evidence grade: Grade B for the underlying diagnostic tools used in the APEX tier (MRI, coronary CT angiography, and standard bloodwork are individually well-evidenced diagnostic technologies). Grade C for the specific company-level outcome claims (ROI, resolution rates), which have not cleared independent peer review.
Human Longevity (Health Nucleus)
Human Longevity is the elder statesman of this category — co-founded by genomics pioneer J. Craig Venter, its Health Nucleus product has been running comprehensive genomic-and-imaging workups since the mid-2010s, long before “longevity clinic” was a mainstream marketing term.
Pricing. The HNX membership starts at $4,950 for the initial year ($2,950 for renewals) and includes whole genome sequencing plus an advanced non-contrast whole-body MRI and several other tests. The HNX Platinum tier costs $25,000 for an initial three-year membership ($6,000 for subsequent years) and adds roughly 15 additional tests on top of the base package — echocardiogram, a two-week wearable heart rhythm recorder, metabolomics, gut microbiome sequencing, DEXA, cognitive testing, and an extensive blood panel of around 120 individual assays. The service has been priced as high as $50,000 in earlier years before settling into its current tiered structure.
Scale. The company remains active in 2026, with around 81 employees and recent expansion into AI-driven longevity research (a new subsidiary, Human Life Foundation Models, announced in May 2026) alongside its consumer diagnostics business.
What they publish. Human Longevity has not published controlled outcome data — such as a trial showing membership reduces mortality or major disease — in a peer-reviewed journal. It is, notably, the one company in this comparison that has been the subject of independent, named critical analysis in a major science publication rather than only trade or marketing press.
What they don’t disclose. In an AAAS Science investigation into the (then-$25,000) Health Nucleus physical, Eric Topol, director of the Scripps Translational Science Institute, called it “the most extensive diagnostic evaluation of people that has ever been done” while explicitly objecting to it being billed as precision medicine screening. Nigel Paneth, a pediatrician and epidemiologist at Michigan State University, was blunter, warning of “psychological damage, high medical costs, unnecessary tests,” and citing “the absence of the slightest shred of evidence that any benefit will accrue to anyone.” Those are two of the most respected independent voices in this field, criticizing this specific product by name.
ScanGlean evidence grade: Grade B for the individual diagnostic components (whole genome sequencing, MRI, and coronary calcium scoring are all real, validated technologies on their own). Grade C for the claim that bundling them into a single-day “precision” workup produces a net health benefit — the specific claim independent critics have pushed back on directly.
Superpower
Superpower is the outlier in this comparison by an order of magnitude: no imaging, no IV therapy, no concierge physical exam — just an annual blood draw, a software layer, and a price that undercuts every other product in this category by a wide margin.
Pricing. $199 per year for the baseline membership (members in New York and New Jersey pay $399 for an expanded 90+ marker panel). This is a significant drop from its original $499/year price at its August 2025 public launch — a roughly 60% cut in under seven months, positioned explicitly around accessibility rather than a premium concierge experience.
What’s included. One comprehensive annual blood draw covering 100+ biomarkers (Quest Diagnostics locations nationwide, or a paid mobile phlebotomy add-on), a personalized health score and biological age estimate, and on-demand messaging access to a care team. Additional testing — Galleri’s multi-cancer blood test, gut microbiome panels, heavy metal and toxin screens — is available at extra cost.
Scale and funding. Superpower has raised $51 million across two funding rounds, most recently $47 million in April 2025 from investors including Forerunner Ventures and Long Journey Ventures.
What they publish. No published outcomes data — clinical or otherwise — was found for Superpower’s specific product. This is, functionally, standard commercial lab testing (the same kind offered by many direct-to-consumer lab companies) wrapped in a proprietary interpretation layer and a lower price than its imaging-heavy competitors.
ScanGlean evidence grade: Grade B for the underlying lab tests themselves (standard, validated blood biomarkers). Grade C for the proprietary “health score” and “biological age” interpretation layered on top, which has not been independently validated in published research.
Next Health
Next Health is the most treatment-focused of the four — less a diagnostics company that happens to offer wellness add-ons, and more a wellness and IV-therapy chain that happens to offer some diagnostics.
Pricing. Three membership tiers: Medicine 4.0 ($99/month — quarterly biomarker and functional testing plus provider consultations), Premier 4.0 ($299/month, the most popular tier — adds two IV vitamin drips and two vitamin shots monthly, cryotherapy, infrared light therapy, hyperbaric oxygen therapy, InBody body-composition scans, and VISIA skin scans), and a Platinum tier with pricing available on request.
What’s included. The core testing layer (quarterly biomarkers, provider consultations) is comparatively conventional. The bulk of what differentiates the higher tiers — IV vitamin infusions, NAD+ therapy, ozone therapy, hyperbaric oxygen, cryotherapy — is treatment, not diagnostics, and is marketed for energy, recovery, and anti-aging purposes that sit outside these therapies’ FDA-approved indications.
What they don’t disclose. Hyperbaric oxygen therapy is FDA-approved for a specific, narrow list of conditions — decompression sickness, carbon monoxide poisoning, delayed radiation injury, chronic diabetic wounds — and Harvard Health explicitly notes that popular off-label uses, including anti-aging applications, “remain scientifically unproven.” No published evidence specific to Next Health’s protocols was found supporting NAD+ IV therapy, ozone therapy, or cryotherapy for longevity or anti-aging purposes.
ScanGlean evidence grade: Grade B for the quarterly biomarker testing layer (standard lab work). Grade C for the IV therapy, hyperbaric oxygen, and other treatment offerings marketed at the higher membership tiers, which is where most of the additional monthly cost sits.
What $199 to $85,000 Actually Buys You
This is the question every one of these clinics’ marketing pages is built to distract you from, and it’s worth answering directly.
The honest starting point is that the individual tests inside these memberships are, mostly, real medicine. Whole genome sequencing, MRI, coronary CT angiography, standard blood biomarkers — these are validated, well-understood technologies with decades of use behind them in appropriate clinical contexts. Nothing in this article should be read as claiming these companies are running fake tests.
What’s much less established is the specific claim that bundling these tests into an annual membership — at any of these four price points — produces a health outcome you couldn’t get by ordering the individually indicated tests through your own physician. Eric Topol, one of the most cited physician-scientists in precision medicine, made this case directly in a 2025 analysis that named nearly every major company in this space, Fountain Life, Human Longevity, and Superpower included: “the ones marketing longevity, healthspan and advanced prevention to consumers have not yet provided any evidence for benefit.” Topol’s specific technical objection is worth understanding, because it explains why more testing isn’t automatically better testing: applying a “kitchen sink” battery of tests to a low-risk, asymptomatic population mathematically amplifies the false-positive rate, a basic consequence of Bayesian statistics that gets lost in marketing copy built around the word “comprehensive.” His example is blunt — “chasing down a lesion on a scan with the complication of the biopsy (e.g. liver bleeding or a collapsed lung) for what turned out to be benign.”
The Human Longevity criticism from Science/AAAS makes the same point from a different angle: Nigel Paneth’s objection wasn’t that the Health Nucleus workup fails to find things — it was that there is “the absence of the slightest shred of evidence that any benefit will accrue to anyone” from finding them at this scale, in this population, outside a controlled study.
None of that means the individual pieces are worthless, or that every member of every clinic in this article is wasting their money. It means the honest framing is closer to: you are very likely buying real, validated diagnostic tools, wrapped in a business claim — “this membership will help you live longer” — that no company here has yet backed with independent, published outcome data, regardless of whether you’re paying $199 a year or $85,000 a year for the wrapper.
Who Should Actually Consider a Longevity Clinic Membership
We’re not going to rank these by “worth it” or “not worth it” for you personally — that depends on your finances, your risk factors, and a conversation with a physician who knows your history. What we can offer is the filter to apply before you sign up for a recurring annual charge.
- Would a physician order these specific tests for someone with my age, sex, and risk profile if I weren’t paying a premium membership fee for them — or am I paying largely for convenience, concierge access, and a nicer waiting room?
- Which parts of this membership are diagnostic tests with independent evidence behind them, and which parts are treatments (IV therapy, supplements, unvalidated “scores”) layered on top with much thinner support?
- What happens, logistically and financially, if something is found? Is follow-up imaging, a specialist referral, or a biopsy included in the membership, or a separate bill on top of it?
- Am I evaluating this company’s own press-released outcome claims, or independently verified data? If a clinic’s core value proposition rests on a statistic, ask where it was published and whether it went through peer review.
- Could I get the individually useful components — appropriate bloodwork, a coronary calcium score if I’m the right age and risk profile, imaging if clinically indicated — through my existing physician, at a fraction of the membership price?
Cost Reality
The annual membership fee is the headline number. It is rarely the whole cost.
- Multi-year commitments. Human Longevity’s Platinum tier is priced as a three-year initial membership, not an easy year-to-year opt-out — evaluate the full multi-year figure, not just the first-year price.
- Follow-up costs live outside the membership. None of the four clinics compared here appear to fully bundle the cost of a specialist referral, a follow-up biopsy, or extended imaging if a scan finds something ambiguous — the single most common outcome of broad screening in an asymptomatic population.
- Add-on creep. Superpower’s $199 base price excludes extra panels (Galleri, gut microbiome, heavy metals); Next Health’s lower tiers exclude the IV and recovery treatments that dominate its marketing; Fountain Life’s CORE tier excludes the imaging that APEX is actually sold on. The advertised entry price is often not the price of the experience being marketed.
- Opportunity cost. At the top of this range, $85,000 a year is a genuine trade-off against other uses of that money — including, for many people, health-relevant ones (a personal trainer, therapy, better sleep infrastructure, or simply guideline-recommended screening ordered through a standard physician) with far more direct evidence behind them.
The Bottom Line
Fountain Life, Human Longevity, Superpower, and Next Health are not the same product at different price points — they’re four different bets on what “longevity” buyers actually want. Fountain Life and Human Longevity are selling comprehensive imaging and genomics under a concierge wrapper. Superpower is selling accessible biomarker tracking, stripped of imaging and price. Next Health is selling wellness treatments with a testing layer attached. All four are, to varying degrees, more expensive versions of things a physician can order individually when they’re clinically indicated — and none of them has published independent, peer-reviewed evidence that the membership itself, as a bundle, extends your life.
That’s not a verdict that any of these companies are frauds. It’s the honest state of the evidence in mid-2026, from a physician-scientist (Topol) and a science journalist’s independent reporting (AAAS), not from a competitor with something to sell you instead.
Frequently Asked Questions
Is Fountain Life worth it?
It depends what you’re buying it for. Fountain Life’s APEX tier ($21,500/year) bundles genuinely comprehensive diagnostics — full-body MRI, coronary CT angiography with Cleerly AI plaque analysis, blood biomarkers — with concierge access. Its outcome claims (a 13-to-1 ROI, 52% of fatty liver cases resolved) are self-published through press releases, not peer-reviewed journal studies, so treat them as a company’s own reporting rather than independently verified results.
How much does Superpower cost?
$199 per year for the baseline membership as of 2026, covering one annual blood draw testing 100+ biomarkers, a personalized health dashboard, and on-demand care team access (members in NY and NJ pay $399 for an expanded 90+ marker panel). Superpower launched at $499/year in August 2025 and cut its price to $199 within about seven months — an unusually large and fast price drop for this industry.
What’s the difference between Fountain Life and Human Longevity?
Both offer imaging-heavy, high-cost memberships, but Human Longevity’s Health Nucleus is the older, more research-oriented model — built around whole genome sequencing paired with full-body MRI, a coronary calcium score, a two-week heart rhythm recording, and gut microbiome testing, starting around $8,000 and reaching $25,000 for its Platinum tier. Fountain Life is newer, more concierge- and lifestyle-oriented, and has grown faster, with over 8,000 members and multiple U.S. locations.
Are longevity clinics worth the money?
Physician-scientist Eric Topol, one of the most cited voices in precision medicine, has written that the companies marketing longevity and advanced prevention to consumers “have not yet provided any evidence for benefit” at a population level. That doesn’t mean no individual member ever benefits from an early catch — it means no clinic in this comparison has published controlled outcome data showing its membership extends life or prevents disease better than standard care, despite price tags that in some cases exceed a new car payment every year.
Is Next Health legit?
Next Health is a real, operating chain of wellness and longevity centers, not a scam — but its most heavily marketed treatments (hyperbaric oxygen therapy for anti-aging, NAD+ IV infusions, ozone therapy) are being used off-label for purposes the FDA has not approved and that Harvard Health and other academic sources say lack solid evidence outside their approved medical uses (like HBOT for decompression sickness or diabetic wounds). Its quarterly biomarker testing is a more conventional, better-evidenced offering than its IV and infrared therapies.
Do longevity clinics take insurance?
Generally no. All four clinics compared here are cash-pay, membership-based models. Some individual tests ordered through a longevity clinic (like a coronary calcium score or standard bloodwork) may be separately billable to insurance if medically indicated, but the membership fee itself is an out-of-pocket wellness expense in essentially every case.
Which longevity clinic has the most evidence behind it?
None of the four has independent, peer-reviewed evidence that its specific membership improves survival or reduces disease compared to standard care — that data doesn’t exist yet for any consumer longevity clinic. What varies is how much of each clinic’s individual components (an MRI, a coronary calcium score, a standard blood panel) are independently well-evidenced diagnostic tools versus unproven add-ons (IV vitamin drips, unvalidated “health scores”, unproven supplement stacks) bundled into the same membership.
What should I ask before joining a longevity clinic?
Ask exactly which tests are included versus billed separately, whether any published or peer-reviewed data supports the specific membership tier you’re buying (not just the company’s general mission), what the follow-up process and cost looks like if something is found, and whether a mainstream physician would order the same tests for someone with your age, sex, and risk profile if you weren’t paying a premium membership fee for them.
This article is for general educational and informational purposes only. It is not medical advice, and it is not a substitute for diagnosis, treatment, or guidance from a licensed physician or other qualified healthcare provider. Pricing and offerings referenced in this article reflect our research as of mid-2026 and are subject to change — see our Methodology page for how we research, grade, and update comparisons like this one. This article does not constitute a personal recommendation to join or avoid any specific clinic. Always consult a clinician before making decisions about screening, testing, or your health.
Disclosure
ScanGlean does not sell memberships, scans, or panels, and we currently have no paid, affiliate, or referral relationship with Fountain Life, Human Longevity, Superpower, or Next Health. If that changes for any provider we cover, it will be disclosed here and on our Methodology page, and it will never influence a provider’s evidence grade or ranking. For more on how the underlying diagnostic tests these clinics bundle actually hold up, see our evidence review of preventive health scans and longevity clinics and our full-body MRI provider comparison.
Sources
- Fountain Life. Membership tiers — CORE, APEX & EPIC, accessed 2026.
- PR Newswire. Fountain Life Redefines Employee Health with Executive Health Program, Delivering $20M Annual ROI and 80% Member Optimization Success, December 2025.
- PR Newswire. Fountain Life Proves the Future of Longevity Is Data, Not Guesswork, January 2026.
- Human Longevity. Pricing — Health Nucleus HNX and HNX Platinum, accessed 2026.
- Science/AAAS. This $25,000 physical has found some ‘serious’ health problems. Others say it has serious problems.
- Topol E. The Business of Promoting Longevity and Healthspan. Ground Truths (Substack), March 22, 2025.
- Superpower. Superpower is now $199, March 2026.
- NutraIngredients. Superpower launches health platform priced like streaming service, September 2025.
- Next Health. Become a Member and Platinum Membership, accessed 2026.
- Harvard Health Publishing. Hyperbaric oxygen therapy: Evidence-based uses and unproven claims.